Hypoxemia

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    Approach to Hypoxemia

    PaO2 < 80

    • Causes of hypoxemia
      • Hypoventilation  (increased PaCO2, normal A-a gradient)
      • Decrease in inspired oxygen  (normal PaCO2, normal A-a gradient)
      • Shunting (normal PaCO2, elevated A-a gradient, does not correct with 100% O2)
      • V/Q mismatch (normal PaCO2, elevated A-a gradient, corrects with 100% O2)
    • To determine cause calculate A-a gradient
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